Wisdom

Wisdom is a deep understanding and realizing of people, things, events or situations, resulting in the ability to choose or act or inspire to consistently produce the optimum results with a minimum of time, energy or thought. It is the ability to optimally (effectively and efficiently) apply perceptions and knowledge and so produce the desired results. Wisdom is also the comprehension of what is true or right coupled with optimum judgment as to action. Synonyms include: sagacity, discernment, or insight. Wisdom often requires control of one's emotional reactions (the "passions") so that one's principles, reason and knowledge prevail to determine one's actions.

Wikipedia

The opposite of wisdom is folly. The opposite of a wise man is a fool.